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Market Cap Distribution

Price Performance Heatmap

5Y Price (Market Cap Weighted)

All Stocks (10)

%
Company Market Cap Price
VRTX Vertex Pharmaceuticals Incorporated 80%
JOURNAVX and VX-993 are NaV1.8 inhibitors, a class of ion channel modulators for pain pathways.
$104.72B
$407.79
-1.34%
NBIX Neurocrine Biosciences, Inc. 60%
Osavampator (AMPA modulator) and other muscarinic/NMDA pathway programs place the company in ion channel/modulator spaces (glutamatergic signaling).
$14.51B
$146.95
+0.38%
AXSM Axsome Therapeutics, Inc. 65%
Some Axsome compounds function via NMDA/ion-channel modulation, aligning with Ion Channel Modulators.
$5.99B
$121.71
-0.66%
ACAD ACADIA Pharmaceuticals Inc. 60%
ACP-711 targets the GABAA-α3 receptor, representing ion channel modulation as a therapeutic approach.
$3.52B
$21.05
-0.94%
XENE Xenon Pharmaceuticals Inc. 75%
Ion channel modulators as a class represent a distinct investable theme given Xenon’s Kv7/Nav1.x programs.
$3.04B
$39.64
-4.34%
BHVN Biohaven Ltd. 92%
Directly applies to Kv7 ion channel modulation and TRPM3 antagonism platforms powering CNS, pain, and neuroimmune programs.
$1.61B
$15.80
-9.97%
RAPP Rapport Therapeutics, Inc. Common Stock 85%
RAP-219 is an AMPA receptor NAM and RAP programs include nicotinic receptor modulators, representing Ion Channel Modulators in CNS.
$967.19M
$26.50
-1.08%
PRAX Praxis Precision Medicines, Inc. 80%
Praxis' small-molecule assets act as ion channel modulators (T-type Ca2+ and Nav channels) to modulate neuronal excitability.
$859.98M
$47.67
-1.37%
CALC CalciMedica, Inc. 92%
Auxora is a CRAC channel inhibitor, positioning CalciMedica as a provider of ion channel modulating therapeutics.
$44.22M
$3.17
-6.36%
MIRA MIRA Pharmaceuticals, Inc. 60%
Ketamir-2 is an oral ketamine analog, which implicates ion-channel/modulator activity (NMDA receptor).
$21.32M
$1.26
-6.67%

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