AstraZeneca Reports Q3 2025 Earnings, Maintains Guidance

AZN
November 06, 2025

AstraZeneca reported third‑quarter 2025 results on Thursday, posting total revenue of $15.19 billion, up 12% year‑over‑year, and a reported earnings per share of $5.10, a 14% increase from the prior year. Core earnings per share rose to $7.04, reflecting a 15% year‑over‑year gain.

The company reaffirmed its full‑year 2025 outlook, targeting high‑single‑digit revenue growth and low‑double‑digit core EPS growth at constant exchange rates. Management highlighted that the guidance remains unchanged despite ongoing pricing pressures and the Medicare Part D redesign.

AstraZeneca’s performance was driven by strong sales in oncology, bioPharmaceuticals, and rare diseases, and the company announced 16 positive Phase III trials this year, including the pivotal data for baxdrostat, Enhertu, and Datroway. The robust pipeline and continued investment in U.S. manufacturing underpin the company’s confidence in sustaining growth.

With revenue and earnings beating consensus estimates, the results reinforce AstraZeneca’s competitive position and support its strategy to deliver an $80 billion revenue target by 2030. The company’s ability to maintain guidance amid regulatory and pricing headwinds signals resilience and a solid trajectory for the next fiscal year.

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