GoDaddy Identifies Top 10 Most Entrepreneurial Cities in the U.S. for 2025

GDDY
November 02, 2025

GoDaddy Inc. revealed its 'Most Entrepreneurial Cities of 2025' report on May 19, 2025, showcasing unexpected hotspots driving the United States' entrepreneurial spirit. The rankings are based on data from the GoDaddy Small Business Research Lab, analyzing cities with the highest number of new ventures created in the previous calendar year.

San Francisco, California, topped the list with 173,054 new businesses, demonstrating a remarkable 122% year-over-year growth. Los Angeles, California, followed with 153,681 new businesses, marking a 50% growth compared to the prior year.

The report highlights that both small and large cities are fueling innovation, with entrepreneurs proving they can succeed anywhere. This data provides valuable insights into the geographic distribution of new business formation, which is directly relevant to GoDaddy's customer base and market opportunities.

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