MiNK Therapeutics Reports Q3 2025 Earnings: Net Loss Widens, Clinical Progress Continues

INKT
November 16, 2025

MiNK Therapeutics, a clinical‑stage biopharmaceutical focused on invariant natural killer T (iNKT) cell therapies, reported a net loss of $2.9 million for the quarter ended September 30, 2025, or $0.65 per share. The loss widened from the $1.8 million net loss ($0.46 per share) reported for the same quarter in 2024, and the company’s earnings per share of –$0.65 beat the consensus estimate of –$0.86 by $0.21, a 24% improvement over expectations. The beat was largely attributable to disciplined operating expenses and the absence of large one‑time charges that had impacted prior periods.

The nine‑month period ending September 30, 2025 saw a net loss of $9.9 million, up from $8.3 million for the same period in 2024. While MiNK remains a cash‑burning, revenue‑free company, the incremental loss reflects increased research and development spending as the agency’s lead candidate, agenT‑797, advances through clinical trials for solid tumors, graft‑versus‑host disease, and severe pulmonary immune failure.

Management guided that multiple clinical programs will be enrolling by the end of 2026, and the company’s cash balance of approximately $14.3 million, supplemented by a $1.2 million equity raise after the quarter, provides a runway through 2026. CEO Jennifer Buell, PhD, emphasized that the company’s progress this quarter “reflects MiNK’s commitment to advancing effective and scalable therapies in cancer and immune‑mediated diseases” and that the platform and partnership expansion “addresses high‑need areas.”

Investors reacted negatively, citing the widening net loss as a concern. The market’s focus on the financial trajectory underscores the tension between MiNK’s promising clinical milestones and the continued cash burn that characterizes early‑stage biopharma companies.

The company’s guidance signals confidence in the near‑term expansion of its iNKT platform, but the increasing losses highlight the need for additional funding to sustain its clinical pipeline. The balance between clinical progress and financial sustainability will be a key factor for stakeholders as MiNK moves toward the next phase of development.

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