Longeveron Secures U.S. Patent for Stem‑Cell Therapy in Female Sexual Dysfunction

LGVN
December 17, 2025

Longeveron Inc. (NASDAQ: LGVN) received U.S. Patent No. 12,496,316 for its proprietary mesenchymal stem cell therapy, laromestrocel, to treat female sexual dysfunction and improve sexual quality of life. The patent, which protects the use of laromestrocel in this indication until 2038, covers a method of administering the therapy to female patients and is based on a clinical‑stage platform that has already earned orphan‑drug and fast‑track designations for hypoplastic left heart syndrome and Alzheimer’s disease.

The grant expands Longeveron’s intellectual‑property portfolio beyond its existing pipeline and signals the company’s continued investment in the allogeneic MSC platform. By securing rights to a new therapeutic indication, Longeveron positions itself to pursue licensing or partnership agreements that could generate additional revenue streams and enhance its competitive advantage in the aging‑related disease space. The company has indicated that it will explore such arrangements, potentially broadening its pipeline and creating new growth opportunities for investors.

Female sexual dysfunction affects up to 46% of women and becomes more common with age, underscoring the unmet medical need that laromestrocel aims to address. The patent’s approval therefore not only protects a novel therapeutic approach but also validates the commercial potential of Longeveron’s MSC technology in a large, growing patient population.

While the patent itself does not translate into immediate sales, it strengthens Longeveron’s market position and may support future funding or partnership discussions. The company’s strategy to expand the therapeutic applications of its MSC platform aligns with its broader goal of developing regenerative solutions for a range of age‑related conditions, positioning Longeveron as a key player in the emerging field of stem‑cell therapies.

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