Masimo announced on June 10, 2025, the findings of a randomized clinical trial published in JAMA Pediatrics, demonstrating significant advantages of Masimo SedLine® Brain Function Monitoring during pediatric anesthesia. The study, conducted by Dr. Yasuko Nagasaka and colleagues, showed improved anesthesia administration in children.
The trial found that EEG-guided anesthesia using SedLine significantly reduced sevoflurane exposure in pediatric patients, leading to a 14% lower incidence rate of pediatric anesthesia emergence delirium (PAED). Patients also regained consciousness 53% sooner and were discharged from the post-anesthesia care unit (PACU) 48% sooner.
These improvements translated into estimated cost savings of $240 to $920 per patient, making pediatric anesthesia safer, more efficient, and more cost-effective. The findings suggest that current fixed sevoflurane dosages may be excessive and advocate for EEG monitoring to minimize anesthetic exposure.
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