On July 3, 2025, Bloomberg News reported that Summit Therapeutics Inc. was in discussions with AstraZeneca PLC regarding a potential licensing agreement for ivonescimab. The deal is reportedly valued at up to $15 billion.
Sources familiar with the matter indicated that the potential partnership could include a multi-billion-dollar upfront payment to Summit, along with significant milestone payments over time. This would provide substantial capital for Summit's ongoing clinical development and commercialization efforts.
The reported discussions highlight the perceived value and potential of ivonescimab, a novel PD-1/VEGF bispecific antibody, in the highly competitive lung cancer market. A partnership with a global pharmaceutical leader like AstraZeneca could significantly accelerate ivonescimab's reach to patients worldwide.
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