Tiziana Life Sciences Withdraws Planned Public Offering, Citing Unfavorable Market Conditions

TLSA
December 15, 2025

Tiziana Life Sciences Ltd (NASDAQ: TLSA) announced the cancellation of its planned public offering of common shares, a move that preserves the company’s existing capital structure and avoids dilution for current shareholders. The decision was made after assessing the equity market environment, which the company described as unfavorable for securing favorable terms.

The company had intended to raise an undisclosed amount of capital to fund its clinical development pipeline, particularly the intranasal foralumab program targeting neuroinflammatory diseases such as multiple sclerosis. By withdrawing the offering, Tiziana will rely on its current liquidity—its current ratio of 1.72 and a debt‑to‑equity of 0.01—to continue supporting ongoing trials while maintaining a strong balance sheet.

Management noted that the market conditions had deteriorated due to heightened volatility in the biotechnology sector and broader equity markets, making it difficult to achieve the pricing and investor demand the company had anticipated. The company remains focused on advancing foralumab and other assets, and the decision reflects a prudent approach to capital allocation.

In addition to the offering withdrawal, Tiziana announced plans to spin off its anti‑IL‑6 receptor monoclonal antibody, TZLS‑501, into a separate publicly traded entity. The spin‑off is intended to sharpen strategic focus and unlock value for shareholders by allowing each business to pursue its own growth trajectory.

The market reaction was mixed. Some investors viewed the avoidance of dilution as a positive, while others expressed concern that the company will not have access to new capital to accelerate its pipeline, leading to a modest decline in investor sentiment.

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