Eli Lilly announced on August 26, 2025, that it will soon ask global regulators to approve its investigational weight-loss pill, orforglipron. This announcement follows a third successful Phase 3 study for the drug. The company's progress solidifies its position as a frontrunner in the oral obesity treatment market.
The impending regulatory submission for orforglipron indicates that Eli Lilly is moving rapidly towards commercialization of its oral weight-loss therapy. This development intensifies the competitive landscape for other companies, including Viking Therapeutics, which are also developing oral GLP-1/GIP agonists for obesity. Eli Lilly's strong clinical data and advanced regulatory status set a high bar for market entry.
For Viking Therapeutics, the news of a major competitor nearing regulatory approval for an oral weight-loss drug is a significant competitive challenge. It underscores the urgency for Viking to demonstrate a differentiated profile for its own oral VK2735 to effectively compete in this rapidly evolving and highly lucrative market.
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